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Some practitioners recommend starting Retatrutide first, allowing the body to adapt to its effects over four to six weeks before adding Sermorelin

Treatment of IC Depending on the symptoms, there is a range of treatment options available for interstitial cystitis

Furthermore, systematic optimization of stimulation protocols, regarding stimulation intensity, duration, repetition rate, targeting, electrode arrangement, and computational modeling based on individual MRI scans to optimize stimulation protocols at the level of the individual might be helpful to increase efficacy of the intervention [243, 244]

As such, the majority of citations referenced in this manuscript originate from local researchers in the DRC and other sub-Saharan African countries as this is where the current expertise related to konzo is most prevalent